Oregon State University

Chromosome Biology

The Chromosomal Basis of Inheritance

I. A chromosome is a single DNA molecule complexed with histone proteins.

A. DNA is highly compacted: DNA + protein = nucleosome structure
Point: chromatin = DNA + histone proteins; coiling

B. By convention, numbering starts with the largest chromosome
Point: Biggest (per microscopy) is first

C. Chromosome landmarks: Via light microscopy, with appropriate preparation, certain regions of the chromosome, are visible via light microscopy and have specific functions. 

  1. Centromere:

  2. Telomere:

 D.  Heterochromatin and euchromatin: terms used to describe the compactness of DNA. 

  1. Heterochromatin: _______________

  2. Euchromatin: _______________

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